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Beta Lactams

Protein Synthesis Inhibitors

Nucleic Acid Inhibitors

Folate Synthesis Inhibitors



The information in this section has been adapted in part from the Australian Therapeutic Goods Association website's repository of product information documents, which are available at https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/PICMI.
 Abu-Gharbieh E, Vasina V, Poluzzi E, De Ponti F. Antibacterial macrolides: a drug class with a complex pharmacological profile. Pharmacological research. 2004 Sep 30; 50(3): 211-22. Agwuh KN, MacGowan A. Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. The Journal of antimicrobial chemotherapy. 2006;58:256-265. Bambeke FV. Glycopeptides in clinical development: pharmacological profile and clinical perspectives.Current Opinion in Pharmacology. 2004;4:471-478. Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. American journal of hospital pharmacy. 1977;34:723. Bhattacharya S. The facts about penicillin allergy: a review. Journal of advanced pharmaceutical technology & research. 2010;1:11-17. Campagna JD, Bond MC, Schabelman E, Hayes BD. The use of cephalosporins in penicillin-allergic patients: a literature review. The Journal of emergency medicine. 2012;42:612. Craig WA. The pharmacology of meropenem, a new carbapenem antibiotic. Clin Infect Dis. 1997; 24(S2): S266-75. Donowitz GR, Mandell GL. Beta-Lactam Antibiotics. N Engl J Med. 1988, 318: 419-426. Dryden MS. Linezolid pharmacokinetics and pharmacodynamics in clinical treatment. The Journal of antimicrobial chemotherapy. 2011;66 Suppl 4:iv7-iv15. Edwards DI. Mechanism of antimicrobial action of metronidazole. J Antimicrob Chemother. 1979 Sep, 5(5): 499-502. Frère JM. Mechanism of action of ?-lactam antibiotics at the molecular level. Biochemical Pharmacology. 1977 Dec, 26(23): 2203-2210. Gonzalez LSI, Spencer JP. Aminoglycosides: a practical review. American Family Physician [H.W. Wilson - GS]. 1998;58:1811. Kielhofner MA. Trimethoprim- Sulfamethoxazole: Pharmacokinetics, Clinical Uses, and Adverse Reactions. Texas Heart Institute Journal. 1990;17(2):86-93. Mazzei T, Mini E, Novelli A, Periti P. Chemistry and mode of action of macrolides. Journal of Antimicrobial Chemotherapy. 1993 Jan 1;31(suppl C):1-9. Müller M. Mode of action of metronidazole on anaerobic bacteria and protozoa. Surgery. 1983;93:165. Neu HC. Third generation cephalosporins: safety profiles after 10 years of clinical use. J Clin Pharmacol. 1990; 30(5): 396-403. Osono T, Umezawa H. Pharmacokinetics of macrolides, lincosamides and streptogramins. The Journal of antimicrobial chemotherapy. 1985;16 Suppl A:151. Reynolds PE, Somner EA. Comparison of the target sites and mechanisms of action of glycopeptide and lipoglycodepsipeptide antibiotics. Drugs under experimental and clinical research. 1990;16:385. Sahai J, Healy DP, Shelton MJ, Miller JS, Ruberg SJ, Polk R. Comparison of vancomycin- and teicoplanin-induced histamine release and “red man syndrome”. Antimicrobial Agents and Chemotherapy. 1990;34(5):765-769. Shinabarger DL, Marotti KR, Murray RW, et al. Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.Antimicrobial Agents and Chemotherapy. 1997;41:2132-2136. Williams JD, Sefton AM. Comparison of macrolide antibiotics. J Antimicrob chemother. 1993; 31 (Suppl C): 11-26.