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Analgesia
 
 

Simple Analgesia

Opioids

Neuropathic Pain Agents

Local Anaesthesia

Other Adjuncts

 
 

Amide Local Anaesthetics

 
 
  •  
    Local / Regional / Epidural
    Bupivacaine
    Marcain 
  •  
    Local / Regional
    Lignocaine
    Xylocaine 
  •  
    Local / Regional / Epidural
    Ropivacaine
    Naropin 

Overview

    • Mechanism of Action

    • Bind to and inhibit neuronal voltage-gated sodium channels, suppressing neuronal depolarization and preventing axonal propagation of action potentials.

Clinical Use

    • Indications

    • Procedural anaesthesia – local anaesthesia, nerve block or epidural block
    • Analgesia – local anaesthesia or epidural block
    • Adverse Effects

    • Hypersensitivity reactions – rash, oedema, anaphylaxis
    • Inadvertent IV administration – agitation, drowsiness, bradycardia, hypotension, ventricular arrhythmia, hyperkalaemia, hypoxia
 
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